Eflornithine- Eflora 15 Gm

Information About Eflornithine- Eflora 15 Gm

About Eflornithine- Eflora 15 Gm

The Medicine Brand Eflora 15 gm is manufactured by Ranbaxy Laboratories Ltd and mainly contents the generic drug Eflornithine.

Pakaging

15 gm

Active Ingredients For Eflornithine- Eflora 15 Gm

Eflornithine 1390

Diseases List For Which Eflornithine- Eflora 15 Gm Is Prescribed

This Drug Is Prescribed For Facial hirsutism in women and african trypanosomiasis

Other Significations For Eflornithine- Eflora 15 Gm

This Medication Eflornithine is the first topical drug for the treatment of unwanted facial and chin hair It does not remove the hair but rather slows its growth The cells surrounding the base of each hair called the hair follicle undergo rapid growth and maturation as they transform into hairs Certain proteins called polyamines are needed for this rapid cell growth and differentiation and the production of these polyamines depends on the activity of an enzyme ornithine decarboxylase ODC Eflornithine is believed to block ODC and thereby slow the growth and differentiation of the cells within the hair follicles Almost 600 patients were studied who routinely had to remove facial hair at least twice weekly and had more than 5 hairs per square centimeter of skin The regrowth of hair was evaluated 48 hours after patients shaved before during and at the end of treatment The patients received either eflornithine cream or a placebo cream twice daily for 24 weeks By the end of 24 weeks of treatment 70 of eflornithinetreated patients had at least some reduction in the rate of hair growth compared with 41 of placebotreated patients Moreover 35 of eflornithinetreated patients had a marked reduction in the rate of growth only minimal darkening of facial skin due to regrowth of hair compared to 9 of placebotreated patients Eflornithine was approved by the FDA in July 2000

Precautions To Be Taken Before Eflornithine- Eflora 15 Gm

No studies have been done to determine if eflornithine interacts with other drugs applied to the skin

Major Conditions And Care

Pregnancy And Eflornithine- Eflora 15 Gm

Can We Take Eflornithine- Eflora 15 Gm During Pregnancy?

Pregnancy Class C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and wellcontrolled studies in humans but potential benefits may warrant use of the drug in pregnant women despite potential risks

Lactation And Eflornithine- Eflora 15 Gm

Can We Use Eflornithine- Eflora 15 Gm During Lactation

Lactation Class L4 There is positive evidence of risk to a breastfed infant or to breastmilk production but the benefits of use in breastfeeding mothers may be acceptable despite the risk to the infant eg if the drug is needed in a lifethreatening situation or for a serious disease for which safer drugs cannot be used or are ineffective

Side Effects Of Eflornithine- Eflora 15 Gm

Nausea stomach upset skin rash acute toxicity

More Danger Effects Fatal Effect Due To Overdose Of Eflornithine- Eflora 15 Gm