Esmeron 50mg Inj
Information About Esmeron 50mg Inj
About Esmeron 50mg Inj
Medicine Brand Esmeron 50Mg Inj is manufactured by INFAR IN and mainly contents the generic drug Rocuronium Bromide.
Pakaging
1
Active Ingredients For Esmeron 50mg Inj
Rocuronium Bromide 50 mg
Diseases List For Which Esmeron 50mg Inj Is Prescribed
This Drug Is Prescribed For -
Other Significations For Esmeron 50mg Inj
This Medication Rocuronium bromide injection is indicated for inpatients and outpatients as an adjunct to general anesthesia to facilitate both rapid sequence and routine tracheal intubation
Precautions To Be Taken Before Esmeron 50mg Inj
Antibiotics Drugs which may enhance the neuromuscular blocking action of nondepolarizing agents such as rocuronium bromide include certain antibiotics eg aminoglycosides vancomycin tetracyclines bacitracin polymyxins colistin and sodium colistimethate If these antibiotics are used in conjunction with rocuronium bromide prolongation of neuromuscular block may occur Anticonvulsants In 2 of 4 patients receiving chronic anticonvulsant therapy apparent resistance to the effects of rocuronium bromide was observed in the form of diminished magnitude of neuromuscular block or shortened clinical duration As with other nondepolarizing neuromuscular blocking drugs if rocuronium bromide is administered to patients chronically receiving anticonvulsant agents such as carbamazepine or phenytoin shorter durations of neuromuscular block may occur and infusion rates may be higher due to the development of resistance to nondepolarizing muscle relaxants While the mechanism for development of this resistance is not known receptor upregulation may be a contributing factor See Warnings and Precautions 59 Inhalation Anesthetics Use of inhalation anesthetics has been shown to enhance the activity of other neuromuscular blocking agents enflurane isoflurane halothane Isoflurane and enflurane may also prolong the duration of action of initial and maintenance doses of rocuronium bromide and decrease the average infusion requirement of rocuronium bromide by 40 compared to opioidnitrous oxideoxygen anesthesia No definite interaction between rocuronium bromide and halothane has been demonstrated In one study use of enflurane in 10 patients resulted in a 20 increase in mean clinical duration of the initial intubating dose and a 37 increase in the duration of subsequent maintenance doses when compared in the same study to 10 patients under opioidnitrous oxideoxygen anesthesia The clinical duration of initial doses of rocuronium bromide of 057 to 085 mgkg under enflurane or isoflurane anesthesia as used clinically was increased by 11 and 23 respectively The duration of maintenance doses was affected to a greater extent increasing by 30 to 50 under either enflurane or isoflurane anesthesia Potentiation by these agents is also observed with respect to the infusion rates of rocuronium bromide required to maintain approximately 95 neuromuscular block Under isoflurane and enflurane anesthesia the infusion rates are decreased by approximately
Major Conditions And Care
Pregnancy And Esmeron 50mg Inj
Can We Take Esmeron 50mg Inj During Pregnancy?
Pregnancy Class : D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans but potential benefits may warrant use of the drug in pregnant women despite potential risks
Lactation And Esmeron 50mg Inj
Can We Use Esmeron 50mg Inj During Lactation
Lactation Class L4 There is positive evidence of risk to a breastfed infant or to breastmilk production but the benefits of use in breastfeeding mothers may be acceptable despite the risk to the infant eg if the drug is needed in a lifethreatening situation or for a serious disease for which safer drugs cannot be used or are ineffective
Side Effects Of Esmeron 50mg Inj
Nausea stomach upset skin rash acute toxicity