Amodep Tm
Information About Amodep Tm
About Amodep Tm
Medicine Brand Amodep Tm is manufactured by FDC Limited and mainly contents the generic drug Amlodipine Besylate.
Pakaging
10
Active Ingredients For Amodep Tm
Amlodipine Besylate 5mg
Diseases List For Which Amodep Tm Is Prescribed
This Drug Is Prescribed For NULL
Other Significations For Amodep Tm
This Medication Amlodipine decreases arterial smooth muscle contractility and subsequent vasoconstriction by inhibiting the influx of calcium ions through Ltype calcium channels Calcium ions entering the cell through these channels bind to calmodulin Calciumbound calmodulin then binds to and activates myosin light chain kinase MLCK Activated MLCK catalyzes the phosphorylation of the regulatory light chain subunit of myosin a key step in muscle contraction Signal amplification is achieved by calciuminduced calcium release from the sarcoplasmic reticulum through ryanodine receptors Inhibition of the initial influx of calcium decreases the contractile activity of arterial smooth muscle cells and results in vasodilation The vasodilatory effects of amlodipine result in an overall decrease in blood pressure Amlodipine is a longacting CCB that may be used to treat mild to moderate essential hypertension and exertionrelated angina chronic stable angina Another possible mechanism is that amlodipine inhibits vascular smooth muscle carbonic anhydrase I activity causing cellular pH increases which may be involved in regulating intracelluar calcium influx through calcium channels
Precautions To Be Taken Before Amodep Tm
Amlodipine Besylate is known to interact with other drugs likeAlcoholAtenololCarbamazepineCimetidine HClDiazoxideDigoxinErythromycinNitroglycerinPhenytoin NaQuinidineRitonavirTadalafilTheophyllineWarfarin Na These interactions are sometimes beneficial and sometimes may pose threats to life Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required
Major Conditions And Care
Pregnancy And Amodep Tm
Can We Take Amodep Tm During Pregnancy?
Pregnancy Class : D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans but potential benefits may warrant use of the drug in pregnant women despite potential risks
Lactation And Amodep Tm
Can We Use Amodep Tm During Lactation
Lactation Class L4 There is positive evidence of risk to a breastfed infant or to breastmilk production but the benefits of use in breastfeeding mothers may be acceptable despite the risk to the infant eg if the drug is needed in a lifethreatening situation or for a serious disease for which safer drugs cannot be used or are ineffective
Side Effects Of Amodep Tm
The severe or irreversible adverse effects of Amlodipine Besylate which give rise to further complications includePeripheral edemaSinus bradycardiaThe signs and symptoms that are produced after the acute overdosage of Amlodipine Besylate include Hy