Larinate 50 Kit
Information About Larinate 50 Kit
About Larinate 50 Kit
Medicine Brand Larinate 50 Kit is manufactured by IPCA Laboratories Ltd and mainly contents the generic drug Artesunate.
Pakaging
1
Active Ingredients For Larinate 50 Kit
Artesunate 50 mg Pyrimethamine 25 mg Sulphadoxine 500 mg
Diseases List For Which Larinate 50 Kit Is Prescribed
This Drug Is Prescribed For Severe malaria including cerebral malaria and as a second line treatment in chloroquine resistant falciparum malaria
Other Significations For Larinate 50 Kit
This Medication Artesunate is a hemisuccinate derivative of the active metabolite dihydroartemisin Currently it is the most frequently used of all the artemesinintype drugs Its only effect is mediated through a reduction in the gametocyte transmission It is used in combination therapy and is effective in cases of uncomplicated P falciparum The dosage recommended by the WHO is a 5 or 7 day course depending on the predicted adherence level of 4 mgkg for 3 days usually given in combination with mefloquine followed by 2 mgkg for the remaining 2 or 4 days In large studies carried out on over 10000 patients in Thailand no adverse effects have been shown
Precautions To Be Taken Before Larinate 50 Kit
This drug should not be used with the following medications because very serious interactions may occur artemetherlumefantrine chloroquine halofantrine ketoconazole quinidine quinine ziprasidoneDo not take halofantrine or ketoconazole for 15 weeks after your last dose of mefloquineTell your doctor of all prescription and nonprescription drugs you may use especially of betablockers eg atenolol propranolol live bacterial vaccines drugs for seizures eg carbamazepine phenytoinvalproic acid drugs affecting liver enzymes that remove mefloquine from your body such as rifamycins including rifabutin and rifampin and azole antifungals including itraconazole and ketoconazole
Major Conditions And Care
Pregnancy And Larinate 50 Kit
Can We Take Larinate 50 Kit During Pregnancy?
Pregnancy Class : D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans but potential benefits may warrant use of the drug in pregnant women despite potential risks
Lactation And Larinate 50 Kit
Can We Use Larinate 50 Kit During Lactation
Lactation Class L4 There is positive evidence of risk to a breastfed infant or to breastmilk production but the benefits of use in breastfeeding mothers may be acceptable despite the risk to the infant eg if the drug is needed in a lifethreatening situation or for a serious disease for which safer drugs cannot be used or are ineffective
Side Effects Of Larinate 50 Kit
Nausea stomach upset skin rash acute toxicity