Lisifen 20 Mg
Information About Lisifen 20 Mg
About Lisifen 20 Mg
Medicine Brand Lisifen 20 mg is manufactured by Cadila Pharmaceuticals Ltd and mainly contents the generic drug Leflunomide.
Pakaging
10 Tablet
Active Ingredients For Lisifen 20 Mg
Leflunomide 20 mg
Diseases List For Which Lisifen 20 Mg Is Prescribed
This Drug Is Prescribed For in active moderate to severe rheumatoid arthritis and psoriatic arthritis
Other Significations For Lisifen 20 Mg
This Medication Leflunomide is an oral diseasemodifying drug that is used in the treatment of rheumatoid arthritis Leflunomide reduces inflammation in the joints that is responsible for both the symptoms of rheumatoid arthritis and the destruction of joints This reduces symptoms as well as the progressive deformities of the joints caused by the arthritis Leflunomide reduces inflammation by suppressing the activity of immune cells responsible for the inflammation Leflunomide suppresses immune cells by inhibiting dihydroorotate dehydrogenase an enzyme that is necessary for the production of DNA and RNA Without DNA and RNA the immune cells and most other types of cells cannot multiply or function or exist Because of its unique and different leflunomide is of value when added to other medications used for treating rheumatoid arthritis Leflunomide was approved by the FDA in September 1998
Precautions To Be Taken Before Lisifen 20 Mg
Cholestyramine Questran Questran Light and charcoal decrease the concentration of the active form of leflunomide in the blood probably by preventing absorption Rifampin increases the blood concentration of the active form of leflunomide by 40 probably by increasing the conversion of leflunomide to its active form This may increase the side effects of leflunomide Increased activity of warfarin Coumadin by leflunomide has been reported rarely Leflunomide also may increase the blood concentration of tolbutamide
Major Conditions And Care
Pregnancy And Lisifen 20 Mg
Can We Take Lisifen 20 Mg During Pregnancy?
Pregnancy Class : C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and wellcontrolled studies in humans but potential benefits may warrant use of the drug in pregnant women despite potential risks
Lactation And Lisifen 20 Mg
Can We Use Lisifen 20 Mg During Lactation
Lactation Class L4 There is positive evidence of risk to a breastfed infant or to breastmilk production but the benefits of use in breastfeeding mothers may be acceptable despite the risk to the infant eg if the drug is needed in a lifethreatening situation or for a serious disease for which safer drugs cannot be used or are ineffective
Side Effects Of Lisifen 20 Mg
Nausea stomach upset skin rash acute toxicity