Synthivan Tab
Information About Synthivan Tab
About Synthivan Tab
Medicine Brand Synthivan Tab is manufactured by Cipla Limited and mainly contents the generic drug Atazanavir .
Pakaging
10 x 1
Active Ingredients For Synthivan Tab
Atazanavir 300mg Ritonavir 100mg
Diseases List For Which Synthivan Tab Is Prescribed
This Drug Is Prescribed For Anti reteroviral drug used in the treatment of HIV Human Immuno deficiency Vurus infection Along with ritonavir it is used for salvage therapy in patients with drug resistance
Other Significations For Synthivan Tab
This Medication Atazanavir is an oral medication that is used for treating infections caused by the human immunodeficiency virus HIV It is in a class of drugs called protease inhibitors that also includes ritonavir Norvir nelfinavir Viracept indinavir Crixivan and saquinavir Invirase Fortovase During infection with HIV the HIV virus multiplies within the bodys cells Viruses are released from the cells and spread throughout the body where they infect other cells In this manner HIV infection is perpetuated among new cells that the body produces continually During the production of the viruses new proteins must be made Some of the proteins are structural proteins that is proteins that form the body of the new viruses Other proteins are enzymes that manufacture DNA and other components for the new viruses Protease is the enzyme that forms the new structural proteins and enzymes Atazanavir blocks the activity of protease and results in the formation of new viruses with defective proteins that are unable to infect the bodys cells As a result the number of viruses in the body the viral load decreases Nevertheless atazanavir does not prevent the transmission of HIV among individuals and it does not cure HIV infections or AIDS
Precautions To Be Taken Before Synthivan Tab
Atazanavir inhibits the enzymes that eliminate many drugs from the body Administration of these drugs along with atazanavir may result in increased concentrations of these drugs and cause more side effects Atazanavir also is eliminated by enzymes in the liver and drugs that increase the activity of these enzymes may decrease the concentration of atazanavir in the blood and reduce the effect of atazanavir Conversely drugs that prevent the elimination of atazanavir may increase the concentration of atazanavir in the blood and cause increased atazanavirrelated side effects Some of the important potential or known interactions are mentioned below Viewers should consult their healthcare provider before combining any drugs with atazanavir Rifampin Rifadin St Johns Wort and efavirenz Sustiva decrease the blood levels of atazanavir and this can reduce the effect of atazanavir Atazanavir decreases the elimination and therefore could increase the side effects of triazolam Halcion midazolam Versed bepridil Vascor verapamil Isoptin diltiazem Cardizem sildenafil Viagra lovastatin Mevacor simvastatin Zocor atorvastatin Lipitor pimozide Orap irinotecan Camptosar cyclosporine Sandimmune rifabutin Mycobutin amiodarone Cordarone clarithromycin Biaxin and ergot drugs Migranal Cafergot Atazanavir is best absorbed under acidic conditions Therefore medications that decrease stomach acidity could reduce the absorption of atazanavir Drugs that decrease stomach acidity include antacids proton pump inhibitors such as omeprazole Prilosec lansoprazole Prevacid pantoprazole Protonix rabeprazole Aciphex esomeprazole Nexium H2receptor antagonists such as cimetidine Tagamet ranitidine Zantac famotidine Pepcid and nizatidine Axid and buffered drugs such as didanosine Videx Individuals who are taking antacids or didanosine should take their atazanavir two hours before or one hour after the didanosine or antacid
Major Conditions And Care
Pregnancy And Synthivan Tab
Can We Take Synthivan Tab During Pregnancy?
Pregnancy Class : D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans but potential benefits may warrant use of the drug in pregnant women despite potential risks
Lactation And Synthivan Tab
Can We Use Synthivan Tab During Lactation
Lactation Class L4 There is positive evidence of risk to a breastfed infant or to breastmilk production but the benefits of use in breastfeeding mothers may be acceptable despite the risk to the infant eg if the drug is needed in a lifethreatening situation or for a serious disease for which safer drugs cannot be used or are ineffective
Side Effects Of Synthivan Tab
Nausea stomach upset skin rash acute toxicity